https://giorgettilab.org/news-1 daily 0.75 2025-09-30 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1572596873583-C3GI9DK37UGYXZJT8U9E/Picture%2B1.jpg news https://giorgettilab.org/news-1/new-preprint-online-loop-extrusion-creates-rare-long-lived-encounters-underlying-enhancer-promoter-communication monthly 0.5 2025-09-30 https://giorgettilab.org/news-1/new-member monthly 0.5 2025-06-04 https://giorgettilab.org/news-1/new-preprint-online-enhancer-control-of-promoter-activity-and-variability-via-frequency-modulation-of-clustered-transcriptional-bursts monthly 0.5 2025-05-12 https://giorgettilab.org/news-1/new-undergraduate-student monthly 0.5 2025-05-12 https://giorgettilab.org/news-1/end-of-the-2024 monthly 0.5 2025-02-04 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/6361f133-8334-466b-a59c-8327b7a22d14/IMG-20241213-WA0017.jpg news - End of 2024 - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/74f96cce-af02-4c14-8074-0c93a032b0c9/WhatsApp+Image+2024-12-12+at+18.51.51_edd5412e.jpg news - End of 2024 - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/cc598002-a966-4865-b157-de0b55390c79/photo_2024-12-13_09-43-36.jpg news - End of 2024 - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://giorgettilab.org/news-1/two-embo-postdoc-fellowships-in-the-lab monthly 0.5 2024-12-13 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/21bc3116-4924-48b4-9e19-071ad20031ae/Verena_Mattia.jpg news - Two EMBO Postdoc Fellowships in the lab - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://giorgettilab.org/news-1/pia-mach-recieved-the-faculty-of-science-prize-for-her-phd-thesis monthly 0.5 2024-12-13 https://giorgettilab.org/news-1/phd-defense-of-jana-tnnermann monthly 0.5 2024-12-13 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/e037938f-42c4-43e4-945b-57a02cd388f0/IMG-20241203-WA0011.jpg news - PhD defense of Jana Tünnermann - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://giorgettilab.org/news-1/greg-wins-a-poster-prize-at-the-embl-conference monthly 0.5 2024-12-13 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/f2e9c34b-c424-4dd2-86d0-55ac1b09ff3b/photo_2024-12-03_11-41-07.jpg news - Greg wins a poster prize at the EMBL conference! - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/764c7a31-a25a-480d-9d5d-8983c67fa8e9/photo_2024-12-03_11-41-06.jpg news - Greg wins a poster prize at the EMBL conference! - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://giorgettilab.org/news-1/giorgettis-lab-at-embl-transcripton-and-chromatin-2024 monthly 0.5 2024-12-13 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1724856674538-918C8QSWJ752HI7ORLRV/DSC_4457.jpg news - Giorgetti lab at EMBL Transcripton and chromatin 2024 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1724856741991-08NHJZV1CAAJR3TQ1C0C/Julie+EMBL2024.jpg news - Giorgetti lab at EMBL Transcripton and chromatin 2024 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1724856741444-CR8IWKPEFSHOX3BDT47V/Kristina+EMBL2024.jpg news - Giorgetti lab at EMBL Transcripton and chromatin 2024 https://giorgettilab.org/news-1/goodbye-to-yomna-gharib monthly 0.5 2024-08-23 https://giorgettilab.org/news-1/annual-lab-barbecue monthly 0.5 2024-08-14 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/165266cb-cdfb-451d-9099-47d41292d617/photo_2024-08-14_11-45-39.jpg news - Annual lab barbecue - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://giorgettilab.org/news-1/new-members monthly 0.5 2024-08-07 https://giorgettilab.org/news-1/new-preprint-online-live-cell-imaging-of-chromosome-folding-inside-tads monthly 0.5 2022-03-07 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/214059a1-d538-466f-bf90-a8c1f1b5d3cb/Screenshot+2022-03-07+at+09.47.43.png news - New preprint online! Live-cell imaging and physical modeling reveal control of chromosome folding dynamics by cohesin and CTCF - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://giorgettilab.org/news-1/we-are-looking-for-master-students monthly 0.5 2021-10-01 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1633086006638-2APB5PB9KJDA67TAHLLA/Picture+1.png news - We are looking for Master students! - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1633086033679-JSQLPQVNLFDRQTE1Z4H6/Picture+12png.png news - We are looking for Master students! - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://giorgettilab.org/news-1/out-deep-learning-method-to-detect-diffraction-limited-is-out-on-nucleic-acid-research monthly 0.5 2021-07-02 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1625237373629-VK9L3VA8Z3WG8WXJYY1Y/b7dc24ce-453d-47c2-a849-f69cd5a88415.jpg news - Our deep learning method to detect diffraction limited is out on Nucleic Acid Research - Make it stand out Overview of deepBlink’s functionality. deepBlink requires a pre-trained model that can be obtained by training from scratch using custom images and coordinate labels (1–3) or downloaded directly (4). To predict on new data, deepBlink takes in raw microscopy images (5) and the aforementioned pre-trained model (6) to predict (7) spot coordinates. The output is saved as a CSV file (8) which can easily be used in further analysis workflows (9). An example use case is shown for a smFISH analysis with blue indicating DAPI staining. https://giorgettilab.org/news-1/new-preprint-nonlinear-control-of-transcription-through-enhancer-promoter-interactions monthly 0.5 2021-04-27 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1619550647809-A4WI3JZ1RZ0OROE6Y42Z/Screenshot+2021-04-23+at+08.55.10.png news - New preprint: Nonlinear control of transcription through enhancer-promoter interactions https://giorgettilab.org/news-1/new-method-deep-learning-method-deepblink-to-automatically-detect-and-localise-spots-in-fish-and-live-cell-imaging-data monthly 0.5 2021-01-25 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1611565770784-UJD8ITJIWCNJHAPNINGI/overview.png news - New preprint! A deep-learning method (deepBlink) to automatically detect and localise spots in FISH and live cell imaging data https://giorgettilab.org/news-1/the-lab-is-growing monthly 0.5 2020-11-03 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1604405313580-VZISP67IIWJAFLZ6K7DL/newPhDstudent.png news - The lab is growing! https://giorgettilab.org/news-1/test-post-1 monthly 0.5 2020-06-26 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593164840040-8BOTYEDUXWDDFS351CI3/MolCell+image+small.png news - Our review on 3C methods and beyond published in Molecular Cell! https://giorgettilab.org/wedding daily 0.75 2025-05-12 https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1413560028518-BSMKJ0TPCS7HWCISX78H/roshni_blog_019.jpg Wedding https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1407190580786-17AQXRVTF19UN5G34FHQ/roshni_blog_035.jpg Wedding https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1406563869276-UHFU7YB4A7MIFLADP5UD/roshni_blog_003.jpg Wedding https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1407190486389-XG016QJFSS8T73X51QT2/roshni_blog_009.jpg Wedding https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1407190449358-8NNS3DPF28AJL5K0LSL3/roshni_blog_027.jpg Wedding https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1406141955462-0ZD9GSYIUBEXQ70GM6E5/image-asset.jpeg Wedding https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1406141972269-5XNOQS87WWZ1OH0ML2E2/image-asset.jpeg Wedding https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1406142011015-F64GK0WBOXWACHF18OWX/roshni_blog_031.jpg Wedding https://giorgettilab.org/location-anya daily 0.75 2025-05-12 https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1407273336113-1NJ9JOPY4HWTQ7J6VS9P/IMG_1232.jpg Location https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1407272210058-IB9T2T3GRS1SROKRUIHW/blog32.jpg Location https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1407273103619-P0WSWRJWZ84PGHU47LUJ/IMG_0604_edit.jpg Location https://giorgettilab.org/research daily 0.75 2024-12-10 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593420118475-BX4V5GEW8VF1EKN4NWZ7/Screenshot%252B2020-06-26%252Bat%252B14.32.27.jpg Research https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593176518882-350F4CV8CC4NNUVNAYP9/model_vv_vv.png Research - Does chromosome structure control gene expression? Several lines of evidence suggest that enhancers control gene expression by forming physical interactions with their target promtoers. However the fundamental principles of how interactions between regulatory sequences are translated into transcriptional outputs are unknown. We try to discover these principles using genomic engineering and experimental methods designed to quantitatively measure chromosome structure and transcription. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/7bb0afe8-fab9-480d-ac87-1f982df21e85/1A2_0min-2.gif Research - How dynamic is chromosome structure? Current understanding of chromosome structure mostly relies on fixation-based techniques, which do not measure the dynamic properties of chromosome structure. Nothing is known on how often an enhancer encounters a promoter during a cell cycle, or how long their interactions last. It is also unknown if transcription occurs simultaneously with enhancer-promoter contacts, or if contacts are actually required to initiate transcription. We study these questions using live-cell microscopy approaches, and use polymer modeling to interpret the data. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593177507208-X8SEH6HA9SLJFYWYGWMM/DamC_vv.png Research - Can we understand long-range transcriptional regulation quantitatively? Our ambition is to discover the basic rules governing how regulatory sequences translate physical interactions into transcriptional outputs. All our experiments are designed to collect quantitative data, which can be interpreted and integrated using mathematical and physical models. We use a range of theoretical and computational tools, from bioinformatics to stochastic modeling and polymer physics. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1591873241634-WG9XP7FQWU1I488T13N2/TADsquare.png Research - Chromosome conformation capture methods https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1591803200391-ZE1KJ7T3TOADPF6G17YM/live_imaging_cropped.png Research - Live-cell imaging https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1591875718829-PZH1I291FUXOIKBYSLJ1/pcr_cropped-mod.jpg Research - Genome engineering https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1591804119301-KAU3LP7GG7WZXBX5COQC/RNAFISH_cropped_mod.jpg Research - RNA and DNA FISH https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593421954119-GNT3NC5T8HSAK6CQG86G/heatmap4website.png Research - Genomics and bioinformatics https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1591875677093-O1CQR1LPNE0H75545F7K/drosophila_cropped_blackBckgr.png Research - Physical modeling https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/0ab5680b-3b41-4bfa-be84-293c982b1e15/SNF_logo_standard_web_color_pos_e.png Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593512463279-ET6LSY7K9BCJIM0UG0SM/ERC_for_site-01.png Research https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593512501535-Z2HU9LWLH572YUI6WMBS/chromdesign_for_site-01-01.png Research Marie Sklodowska-Curie Innovative Training Network (ITN) “Chromdesign” https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593512524874-8NAED98MUU8TYM390ZS1/pept-net_for_site-01-01.png Research Marie Sklodowska-Curie Innovative Training Network (ITN) “PEP-NET” https://giorgettilab.org/new-page daily 0.75 2025-09-30 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1591856773709-3V9ZH7P1RZOVYLOE68MB/pcr.png Publications https://giorgettilab.org/lab-members daily 0.75 2026-02-04 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593421698019-JN8YMQLHJRVXW8WRMI6A/20200518_RNA_FISH_modified.jpg Lab members https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/813c0a70-e68d-4c09-9d7d-bf73070ad9b0/250519_FMI_Portraits_Luca_Giorgetti+6_small.jpeg Lab members https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1604302169931-KW2K80EC0LDQVGBCOWVL/Gergely_cropped.png Lab members https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/f2b47e75-22cb-4773-887d-a8b1821bee6d/croped_julie_cordier.jpg Lab members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/38cd3e02-fb60-4833-b6f6-c350130fc512/Testoni%2C+Elena_web.jpg Lab members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/100b0483-9653-42db-a940-8923a72545b8/Louafi%2C+Nessim_edited.jpg Lab members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/da840975-3d8a-43a4-9395-bdac47d63005/Jonas.png Lab members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/cbf15489-325c-4bbb-8407-be97ecac0bd4/Fliamer_Ilia_8717_cropped.jpg Lab members https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/ef483bde-98f0-4ee6-9f82-4cca4be3890d/kristina_web.jpg Lab members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/0aa4e5c7-7ea3-4696-9dc3-6911ab1ab1f2/Asset+2.png Lab members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/285771c9-5315-475a-a85f-462209ccc2ba/verena.png Lab members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1591281539195-XJ6W5S0MXLJNVO3LNOMT/Julie_cropped.png Lab members https://giorgettilab.org/resources daily 0.75 2020-07-02 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593422146598-ZD4TZLJD8SBMBYQN8AG4/sequence.jpg Resources https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1588856716047-5UAFOROGFGDYU0T3QGF6/GitHub-Mark-120px-plus.png Resources https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1591857560158-TPM3RX0ML8AUYQGNTFZH/DamC_scheme.png Resources https://giorgettilab.org/contact daily 0.75 2024-08-07 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1591874223954-8GVJG02PQSRM4HD0GSTS/index-banner_ver4.png Contact https://giorgettilab.org/home daily 1.0 2020-06-29 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1600093619815-KVW551C77AASI70WBBAU/index-banner_ver4.jpg Home https://giorgettilab.org/resources-1 daily 0.75 2020-07-02 https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1593422146598-ZD4TZLJD8SBMBYQN8AG4/sequence.jpg Resources with nanopore https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1588856716047-5UAFOROGFGDYU0T3QGF6/GitHub-Mark-120px-plus.png Resources with nanopore https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1591857560158-TPM3RX0ML8AUYQGNTFZH/DamC_scheme.png Resources with nanopore https://images.squarespace-cdn.com/content/v1/5dbbeaad6286de63cbfd93fd/1592202687566-R7S3IQ4GCLIE2KBQI96B/20200122_nanopore_cassette252_135_cropped.png Resources with nanopore https://giorgettilab.org/gifts-anya daily 0.75 2025-05-12 https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1406564564563-SSABRBGY6ZDICG2M0TWU/roshni_blog_022.jpg Gifts https://giorgettilab.org/read-me-anya daily 0.75 2025-05-12 https://images.squarespace-cdn.com/content/v1/53cfdbf9e4b09d5219fcc098/1407965662287-JGJDENV4XN2FWVPAW7MD/roshni_blog_020.jpg Read Me